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Wiyoungjin

Sep 29, 2025

Rejuran HB one-week change

Rejuran HB one-week change

Rejuran HB one-week change

The change of rejuvenation that has become less painful



Hello.

This is Director Wi Yeong-jin.

No matter how hard I apply high-end cream,

the dryness that pulls from within cannot be resolved.

Have you ever felt truly helpless?




As the dryness inside the skin gradually resolves,

I felt the fine wrinkles soften.



Those who have experienced Rejuran HB

often mention the changes they notice first,

which is exactly this aspect.

Improvement starts not from the surface,
but deep within the skin.

Today, I will summarize the actual effects of Rejuran HB

and the skin changes that occur one week after the treatment

based on real testimonials.





How does it work?



This is a method where

PN (polynucleotide, the key substance that helps skin recovery)

is inserted into the dermal layer of the face.


That’s why it is commonly referred to as the salmon injection,

but strictly speaking, the salmon injection refers to PDRN injection, and

Rejuran HB is classified as a PN injection.

For those with sensitive skin, concerns about fine lines, or

trouble caused by decreased elasticity,

this can be an excellent alternative.




In summary,


it is a procedure that enhances the skin’s self-recovery ability
and creates a healthy internal environment.








Effect Comparison by Injection Method


There are two main methods for administering the injection.


  1. Hand Injection


The hand injection is performed by a specialist

who precisely delivers the medication to each area

in the dermal layer.

Compared to equipment use,

the drug loss rate, that is, the loss rate, is relatively low.

In simple terms,

if the drug leaks less during the injection process,

the actual efficacy of Rejuran HB is

better demonstrated.



Those who prefer hand injections

especially focus on this loss rate.



  1. Device Injection


The device injection uses a machine to

inject the PN components into the dermis.

Compared to hand injection,

it distributes the medication more evenly,

making fine adjustments easier.

Also, the needle thickness is small,

which reduces the pain intensity.




Ultimately, it's not that one side is necessarily better than the other;
the key is to choose the method that suits you best.






Timing of Effect Manifestation and Duration



Many people are curious about

when the effects of Rejuran HB become visible.

This is one of the most common questions

asked in the clinic.




About 2 weeks after treatment, I noticed

that the skin texture had clearly

become smoother.




✨State Immediately After Treatment


The embossed marks seen immediately after Rejuran HB treatment are


signs that the medication was accurately injected at the correct depth.


You can see this as a process indicating that

the treatment was performed correctly.



On the day of treatment, you may also feel

a temporary improvement as the skin

becomes moist or like its texture is refined.



However, these changes are

responses to the physical effects of the injected drug.



Over time, the skin will start to

promote collagen production,



The gradual recovery of the skin's internal environment
is the key change that occurs.



During this process, the skin's

elasticity, density, and health will naturally improve.


Therefore, it is difficult to judge the effect of

Rejuran HB solely based on the changes felt immediately after treatment.


What you see now is just the beginning stage,

and future skin changes are more important.








✨2-Week Milestone

About 2 weeks after treatment,

you can start to expect some skin improvements.

And between 2 to 4 weeks,

the full effects will appear,

generally lasting between 6 months to a year.

※ This is based on receiving 3 or more treatments.

However, the timing of effect manifestation and duration after Rejuran HB treatment

can vary according to individual skin condition or

health status, so please remember this.

When you consult,

checking your skin condition in detail

can provide a more accurate prediction of effects.





Recommended Treatment Frequency



When I explain like this,

many people ask, "So do I only need to get it once every 6 to 12 months?"

In my opinion,

it would be best to carry out 3 treatments initially at one-month intervals,

and afterwards, receive maintenance treatments every 3 to 4 months

to maintain the effects of Rejuran HB for a longer time.



The frequency can be adjusted according to your skin situation,

so feel free to take note.





Main Summary Today



🔹 PN components help restore skin elasticity and alleviate internal dryness
🔹 Accurately injecting into the dermal layer is the key
🔹 Effects begin to show gradually from 2 to 4 weeks after treatment
🔹 Rejuran HB effects should be stabilized by receiving at least 3 treatments
🔹 The effects of Rejuran HB can last about 6 months to 1 year depending on individual skin condition








Today, I summarized the timing of effect manifestation

and related content after Rejuran HB treatment.

I hope this has been of some help.

This was Wi Yeong-jin.

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Direct Columns Written by Directors Wi Young-jin, Kim Jang-ju, Kim Ha-won, and Kim Ga-eul

Honest and sincere description of skin beauty treatments

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