What is Human ADM Dermis Anyway?
Is Human ADM Skin Booster Really Okay?
Hello,
Chief Director Kim Ga-eul here.
As of January 2026
there is a skin booster that has seen a particularly sharp increase in inquiries in the dermatology market.
Has the stock also skyrocketed?
It seems to be a very hot issue.
Yes
To be honest, I was in a position of "let's wait and see" when the Allogeneic Dermis Skin Booster first came out around June of last year (June 2025).
-About half a year since its release
-Clinical cases accumulated in various hospitals
-Actual procedure data and responses have been reliably accumulated
Based on this information,
I believe it has now entered the ranks of the hottest
next-generation skin boosters in 2026.
Before/after photos of the procedure
And currently at Beautystone,
stable demo progress and successful long-term follow-ups
are being applied in actual procedures.
Today, let’s look at
the Human ADM Skin Booster
and especially check out the three major products commonly mentioned below.
CellREDM/Rituo/Juveacell
What is Human ADM (Acellular Allogeneic Dermis)?
The name is quite difficult, so what exactly is Acellular Allogeneic Dermis?
Breaking down the terms makes it easier to understand.
Allogeneic Dermis
>>> Human skin
Acellular
>>> To avoid immune reactions!
In other words>>
This is tissue from human skin with the cells removed, leaving only the structure.
Look at the effects below
Improvement in volume and skin texture.
You can see that the sunken areas have improved quite a bit, right?
[ Components of Allogeneic Dermis ]
1.Collagen
2.Elastin
3.Glycosaminoglycans (GAGs)
These components are responsible for
skin elasticity, moisture, and structure.
(*ECM (Extracellular Matrix))
Is the safety of Acellular Allogeneic Dermis okay?
Honestly, many people’s first thought is that.
Injecting someone else’s skin?
I had the same concerns at first.
However, this component is not a completely new concept.
It has been used without significant issues for a long time.
In plastic surgery, it has been used for decades for:
1. Skin reconstruction for burn patients
2. To prevent transparency over implants in nose and breast surgeries
using allogeneic dermis products (e.g. Megaderm).
Now, it has evolved into the form used for 'skin regeneration and elasticity improvement'.
That is the Allogeneic Dermis Skin Booster.
Advantages and disadvantages of Human ADM Skin Booster
Why is it trending? (Advantages)
If you look at the products that have led the skin booster market in recent years,
they share a common point!
[Juvelook, Sculptra, Radiesse]
Very important!
Methods that “induce” collagen production
(Inflammatory reaction → Collagen production)
In contrast, Acellular Allogeneic Dermis is different.
Rather than stimulating collagen production,
it is a concept of directly providing the collagen structure itself.
So
1. There are fewer inflammatory reactions
2. High biocompatibility
3. Very natural results.
The expected effects are as follows:
Improvement in skin texture and tone
Increased skin elasticity
Reduction of pores and fine lines
Improvement in dehydration
Reduction of redness
Supplementing very natural volume
Then, are there no disadvantages?
Psychological barriers
Some people feel discomfort because it involves “someone else's skin tissue.”
Ethical issues are sometimes mentioned,
but all tissues are managed through a legitimate donation system.
2. Embossing (temporary unevenness)
If injected too shallowly, the skin may become bumpy right after the procedure.
However, since this is not an inflammatory nodule, it usually disappears naturally within a few weeks.
[*There are hardly any nodules due to immune reactions (like Juvelook and Sculptra).
3. Volume limits
There is some absorption process, and since the volume naturally increases afterward,
it may feel slightly lacking in terms of adding volume compared to injections that induce collagen through inflammatory reactions, such as hyaluronic acid fillers, Sculptra, and Radiesse.
4. Price
Since one needs to use a whole unit,
the procedure price usually ranges from 600,000 to 800,000 won,
which can be a resistance factor.
Comparison of the three major Human ADM Skin Boosters
Currently, there are a total of three types of products being used in the country.
The order of release is Elavie Rituo / CellREDM / Juveacell.
Various products from other companies are also expected to be released in the future.
It is important to understand the respective positions and characteristics
rather than which product is better.
① Elavie Rituo (Re2O)
Manufacturer: LNC Bio (the top human tissue processing company in Korea)
Sales: Humedics
Particle size: approximately 100µm
Position: Original / Most clinical data
Disadvantage: Supply is insufficient compared to demand.
② CellREDM (CellREDM)
Manufacturer: HansbioMed (the first AATB certified in Korea)
Particle size: approximately 75µm (more refined)
ECM content: 160mg (most abundant)
Smaller particles
→ Increased collagen production efficiency
→ Allows for thinner needles (less pain)
③ Juveacell (Juveacell)
Manufacturer: Doff / Sales: Vaim (manufacturer of Juvelook)
Features:
Supercritical carbon dioxide extraction method (no chemical agents used) - high ECM extraction efficiency
Released in already hydrated state - convenience of use, prevention of clumping
Advantage: gentler and reduced risk of clumping
Disadvantage: no AATB certification / low ECM content
My Conclusion!
Can Human ADM Skin Booster become the main stream of the market like Rejuvenate and Juvelook?
I think it has sufficient advantages.
Rather than stimulating the skin to produce collagen, it is about reinforcing the structure.
In the end, the advantages are natural and stable skin improvement,
making it suitable for those who want "a natural improvement in skin without it being noticeable."
However, it is not necessarily the answer for all skin types,
so it is most important to choose after a thorough consultation with a doctor regarding skin condition, goals, and past treatment history.
This has been Kim Ga-eul.
