What is Human ADM Dermis Anyway?
Is Human ADM Skin Booster really effective?
Hello,
This is Chief Director Kim Ga-eul.
As of January 26
there is a skin booster that has seen a significant increase in inquiries in the dermatology market.
Stocks have also surged?
It seems to be a very hot issue.
In fact, when the allogenic dermis skin booster first came out around June last year (June 25),
I initially thought, "Let's wait a bit longer."
-It has been about half a year since its release
-Clinical cases have accumulated in various hospitals
-Data and responses from actual treatments have been steadily building up
Based on this information,
[Effect of Cellredm on the Temple Area]
I believe it has now risen to the rank of the hottest next-generation skin booster for 2026.
Before/after treatment photos
And currently, at Beautystone,
stable demos and long-term tracking observations have been successful,
and it is being applied in actual treatments.
Today, I would like to talk about
the Human ADM Skin Booster,
specifically about the three major products commonly mentioned.
Cellredm/Rituo/Juveacell
What is Human ADM (Acellular Allogenic Dermis)?
The name is quite difficult; what is acellular allogenic dermis?
If we break down the terms, it becomes easier to understand.
Allogenic Dermis
>>>Human skin
Acellular
>>>To prevent immune reactions!
That is>>
An organization that has had the cells removed from human skin, leaving the structure.
See below for the effects
Improvement in volume and skin texture.
You can clearly see the improved areas, right?
[Components of Allogenic Dermis]
1.Collagen
2.Elastin
3.Glycosaminoglycans (GAGs)
These components are responsible for
skin elasticity, hydration, and structure
(*ECM (ExtraCellular Matrix)).
Is the safety of acellular allogenic dermis alright?
Honestly, this is the first thought that comes to many people's minds.
Are you really injecting the skin of another person?
I also had the same concern at first.
However, this concept is not entirely new.
It has been used without major issues for a long time.
In plastic surgery, for decades,
1.Burn patients' skin reconstruction
2.Preventing visibility over implants in nose and chest surgeries
allogenic dermis products (e.g., Megaderm) have been used.
Currently, it has evolved to be used for 'skin regeneration and elasticity improvement'.
The acellular allogenic dermis skin booster is exactly that.
Advantages and Disadvantages of Human ADM Skin Booster
Why is it trending? (Advantages)
Looking at the products that have led the skin booster market over the past few years,
there is a commonality among them!
[JuveLook, Sculptra, Radiesse]
Very important!
The method induces collagen production.
(Inflammatory response → Collagen production)
On the other hand, acellular allogenic dermis is different.
It does not stimulate collagen synthesis but directly injects the collagen structure itself.
Thus,
1. There is less inflammatory response,
2. It has high biocompatibility,
3. The results are very natural.
The anticipated effects are as follows:
Improvement in skin texture and tone
Increased skin elasticity
Reduction in pores and fine lines
Improvement in underlying dryness
Reduction in redness
Very natural volume enhancement
Are there any disadvantages?
Psychological barrier
Some people feel rejection because it involves 'skin tissue from someone else'.
Ethical issues may be raised, but
all tissues are managed through a legal donation system.
2. Embossed appearance (temporary irregularities)
If injected too superficially, the skin may become uneven immediately after the treatment.
However, since these are not inflammatory nodules, they generally disappear naturally within weeks.
[*There are almost no nodules resulting from immune reactions (like Juvelook, Sculptra).
3. Volume limitations
There is some absorption process, and then the volume naturally increases,
so compared to hyaluronic acid fillers or injections that induce collagen through inflammatory responses like Sculptra and Radiesse,
it may feel slightly lacking in increasing volume.
4. Price
Since one must use the entire unit,
the high treatment price of 600,000 to 800,000 won can
be a deterrent.
Comparison of the Three Major Human ADM Skin Boosters
Currently, there are a total of three types of products used in Korea,
which were released in the order: Elavie Rituo / Cellredm / Juveacell.
Diverse products from other companies are expected to be released later.
Rather than which product is better,
it is essential to understand each one’s position and characteristics.
① Elavie Rituo (Re2O)
Manufactured by: L&C Bio (Korea's No. 1 human tissue processing company)
Sold by: Humedics
Particle size: About 100µm
Position: Original / Most clinical data
Disadvantages: Supply shortage compared to demand
② Cellredm (CellREDM)
Manufactured by: Hans Bio Med (Korea’s first AATB certified)
Particle size: About 75µm (finer)
ECM content: 160mg (most)
Smaller particles
→ Higher collagen synthesis efficiency
→ Use of finer needles possible (less pain)
③ Juveacell (Juveacell)
Manufactured by: Dope / Sold by: Biome (Juvelook manufacturer)
Features:
Supercritical CO2 extraction method (No chemical agents used) - High ECM extraction efficiency
Released in a hydrated state - Ease of use, prevention of clumping
Advantages: Softer and less clumping risk
Disadvantages: No AATB certification / Low ECM content
My Conclusion!
Can Human ADM skin booster become mainstream in the market like the existing Rejuran and Juvelook?
It seems to have sufficient advantages.
Rather than stimulating the skin to produce collagen, it has the concept of reinforcing the structure,
and ultimately, its advantages are natural and stable skin improvements,
making it suitable for those who want "unnoticeable skin improvement".
However, it is not an absolute answer for all skin types,
thus it is crucial to choose carefully after sufficient consultation with a doctor regarding skin condition, goals, and existing treatment history.
This is Kim Ga-eul.
